Launched this month in Brazil, the herpes simplex vaccine is now available in private clinics across the country. The disease appears late in people who have chicken pox, which often affects people over the age of 50 or patients with immune system disorders. It should be given in two doses, with an interval of two months between applications.
Shingrix received regulatory approval from the National Health Surveillance Agency (Anvisa) in August 2021 for the prevention of herpes zoster in adults 50 years of age and older and adults 18 years of age and older, and the incidence of the disease is increasing. At risk, such as patients with immune system. People undergoing treatment for cancer, people living with HIV, people undergoing a bone marrow or organ transplant, lupus, multiple sclerosis, among others.
The cost of each application on the private network is approximately R $ 843. With two dosing procedures, with two-month intervals, the total cost is approximately R $ 1,686. In addition to technology, changes in the exchange rate also appear on the final price of the immunizer. According to pharmaceutical company GSK, the price may vary according to the price practice of ICMS and private clinics in each region of the country. Vaccine distribution has begun, with substantial supplies forecast for July across Brazil.
“It is undeniable that the impact of new technologies on vaccine development has led to significant advances in population health. But technologies are expensive, so vaccine prices today make access difficult, especially in Brazil, which There is a big difference in the exchange rate. Important “, explained Geraldo Barbosa, President of the Brazilian Association of Vaccine Clinics (ABCVAC), while emphasizing that its use in prescription and prescription. Should be adapted to the package entry.
In addition to pain, soreness and skin lesions, herpes zoster, also called shingles, can have serious consequences. If left untreated, the disease can cause serious complications, affecting the eyes, ears, and facial nerve endings, leading to paralysis, hearing loss, and visual impairment. In Brazil, the subject becomes even more relevant, given the 35.4% increase in reported cases of the disease, which was observed during the COD-19 epidemic.
“This person has had chicken pox or chicken pox, no matter when, but usually in childhood, and after the medical picture has passed, the virulence zoster virus is as if he has fallen asleep at a nervous end. At some point, in general, in the elderly, the zoster manifests itself. And when that happens, it usually loses its nervousness completely, “said President of the Brazilian Society of Immunizations (Sbim). Juarez Kanha says.
Shingrix is more than 90% effective in people over the age of 50, at a time when the virus often begins to attack. In the 50- to 69-year-old age group, the efficacy reaches 97%. The chances are high. In the case of Zostavax, the pharmaceutical company MSD’s previous generation vaccine, which was less effective, was also not allowed to be used. “It was a weak vaccine with an interesting efficacy, but it was getting smaller as the person got older. Are
Shingrix is a inactive vaccine used in other countries, such as the United States. “The advantage is that it can be applied to immunocompromised patients and is licensed from the age of 18. And, of course, we recommend it for people between the ages of 18 and 50 who have the disease. There is some risk. In general, patients with weakened immune systems and conditions that pose a risk of zoster, such as diabetes. It is recommended as a routine vaccine for people over the age of 50. ” Says Juarez. In addition, the new vaccine protects against a serious complication of shingles, post-herpetic neuralgia, a disease that causes vesicles (skin bubbles) that cause severe pain.
In addition to Brazil, Shangrix is already licensed for use in the European Union and several countries, such as the United States, Canada, Japan, China, New Zealand, Singapore and Australia. “It is already available in many countries and is highly effective for people over the age of 50. In addition, it is a vaccine that is safe for people over the age of 18 who have an immune system.” “Because it is not made up of live viruses,” says Gunnar Rediger, GSK BioTech business unit leader.
Currently, no vaccine is available in the Unified Health System (SUS).
What is herpes zoster?
Herpes zoster or shingles is a disease caused by the varicella zoster virus, which also causes chicken pox. The virus stays inactive throughout a person’s life.
Reactivation occurs in adolescence or in people with immunological disorders, such as those with chronic diseases (hypertension, diabetes), cancer, AIDS, transplant recipients, among others.
Uncommonly, there are patients who develop herpes zoster after contact with patients with varicella and even after contact with other zebrafish patients, which indicates the possibility of re-infection in a person who Immunizations have already been given. It is also possible for a child to have chicken pox in contact with a zebrafish patient.
The disease can lead to complications and other serious medical forms, including death.
What are the symptoms?
The medical picture is almost always normal. In most cases, the following symptoms appear before the skin lesions:
– Nervous (nervous) pain
– Paresthesias (tingling, tingling, numbness and pressure)
– Local irritation and itching
How is the diagnosis made?
Diagnosis is made easily because lesions affect nerve endings. It starts with itching, itching and then progresses to sores. Many skin lesions called vesicles (small blisters on the skin) break down and heal.
Other complications are post-herpetic neurology, a severe pain condition that lasts for many years. If it affects the nerves of the face, it can also damage vision.
How is the treatment done?
The sooner the diagnosis is made, the better the response to treatment. In general, with the use of antivirals. A bactericidal, non-salicylate analgesic, and systemic antihistamine may be given to remove pruritus (pus).
What are the precautions?
– Vaccination (Children are vaccinated against chicken pox at 1 year and 3 months and then at 4 years of age. Sensitive teens and adults who have not had chicken pox should be vaccinated. Protects against chicken pox. Yes – there is no zest without chicken pox).
– Wash your hands after touching the wounds.
– Isolation: Children with uncomplicated chicken pox should return to school only after all lesions have become itchy. Children who have a weakened immune system or have a long clinical course should return to activity only after a vascular rupture.