Unprecedented initiative in Brazil to create a genetic database of SUS patients

Support Program for Institutional Development of the Unified Health System (PROADI-SUS), Will collect data from the Ministry of Health. Genomics And for the unprecedented construction of such a database in Brazil, 2,382 oncology and cardiology patients were treated at SUS. In addition, 2,000 military police officers in Rio Grande do Sul will be genetically engineered for arterial hypertension, as well as qualifying 300 professionals working in genomic and precision medicine and public health. ۔ This initiative will have a national impact and will be led. BP – Beneficia Portuguese Hospital of Sao Paulo, a health center that is also part of Pradi, in partnership with the University of Sao Paulo (Instituto do Coração of the Faculty of Medicine of the University of Medicine, the Hospital das Clکاncas)InCor/HCFMUSP).

Named “Mapa Genome Brasil – Precision Medicine in Oncology and Cardiology in the SUS”, the project will contribute to Brazil’s genome program, launched by the federal government in 2020 with the aim of developing scientific and technological advances in the fields of genomics and health. To encourage development. Accuracy within the scope of SUS. The data collected through the Brazilian genome map is expected to contribute to the implementation of population management strategies in breast cancer, colorectal cancer, prostate cancer and cardiovascular diseases, all of which are linked to chronic non-communicable diseases ( NCDs). According to Renato Vera, Executive Director of Medical, Technical and Education and Research Development, the project will create more knowledge about how pathologies develop and how they behave in populations, making them increasingly effective. It will help in the development of treatment as well as prevention. Strategy

“Today, when working with research or analysis of genetic sequencing, care routines, our professionals are based on a database of American or European populations, and Brazil is a country of continental dimensions and characteristics that The Brazilian genome map is a strong and detailed proposal that will bring unparalleled information to the Brazilian population, which will directly affect the care of patients in SUS. Combined with knowledgeable, solid and well-compiled databases, the drug is allowed to operate in a personalized and highly efficient manner, both from a new treatment and from an individual prevention perspective for at-risk patients. This study is a great opportunity to identify genetic factors in the development of chronic non-communicable diseases (NCDs) in our population, “said the director.

By the end of 2023, the genetic material of patients and family members will be analyzed, including 110 from breast cancer, 50 from colorectal cancer and 22 from prostate cancer, located in eight health centers across the country. Are Sensitivity to these diseases will be assessed through identified variants. It is important to emphasize that research participants will go through personal services.

Genetic sequence for hypertension

By July 2022, the genetic risk for arterial hypertension will be classified in a group of 2,000 military police officers based in Pilotas (RS) to actively track people with increased genetic risk. Through the implementation of the military strategy model. And complex heart disease.

“The results of this study will, in an unprecedented way, determine the genetic risk of the population for these cases, which will allow the discovery of new associated biomarkers. At the same time, the resulting information The algorithms will be incorporated to increase their effectiveness and predictive power, which is essential for designing anticipated strategies on a common disease with high morbidity and mortality.

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